COPIED
4 mins

INGREDIENT FOCUS

SPOTLIGHT ON… ASTAXANTHIN

Ellen Cummings explores the magic behind astaxanthin’s ability to enhance skin health, improve elasticity and defend against environmental stressors

Astaxanthin is gaining attention for its multi-layer antioxidant protection, barrier support and anti-ageing properties, but how does this trending ingredient work?

WHAT IS ASTAXANTHIN?

Astaxanthin is a naturally occurring red-orange carotenoid antioxidant, primarily produced by microalgae such as Haematococcus pluvialis. It is also found in lower concentrations in red seaweed (Rhodophyta) and gives salmon, shrimp and flamingos their signature pink hue.

Candice Gardner, education manager at Dermalogica UK, explains, “In skincare, it’s celebrated for its ability to help defend the skin against oxidative stress caused by UV exposure and pollution.”

Debbie Thomas, founder of D. Thomas Clinic and Cellis skincare, adds, “In skincare, it’s sourced directly from this algae for use in creams, serums and gels.”

HOW IS ASTAXANTHIN SOURCED AND STABILISED?

For professional skincare use, astaxanthin is most commonly derived from sustainably cultivated microalgae grown under controlled conditions. The pigment is carefully extracted and stabilised to preserve potency and colour integrity, often via encapsulation methods such as liposomes, nano-emulsions or polymers.

“Opaque or airless packaging is essential to maintaining ingredient integrity,” notes Thomas.

This careful sourcing ensures the ingredient is vegan, traceable and renewable – aligning with responsible formulation practices in modern skincare.

WHAT SETS ASTAXANTHIN APART FROM OTHER ANTIOXIDANTS?

Astaxanthin’s unique molecular structure allows it to span both the lipid and aqueous layers of cell membranes, providing broader antioxidant coverage than vitamin C or E.

Gardner explains, “Vitamin E can protect the lipid cellular membrane structures whilst vitamin C provides aqueous antioxidant defense in surrounding areas. They can work collaboratively, however astaxanthin offers an all-in-one solution.”

Thomas adds, “Astaxanthin sits across the skin’s lipid membranes and neutralises the reactive oxygen species that kick off UV and pollution damage right at the cause. That placement gives it strong singlet-oxygen quenching, steady performance and less sting.”

This makes astaxanthin highly effective at protecting DNA, reducing oxidative stress and maintaining skin resilience.

HOW ASTAXANTHIN WORKS IN THE SKIN

Astaxanthin integrates into cell membranes, neutralising free radicals before they can damage lipids, proteins or DNA. Beyond its antioxidant activity, it acts as a signalling molecule, influencing pathways involved in inflammation, collagen synthesis and cellular repair.

“By reducing that oxidative ‘spark’, it helps keep keratinocytes and fibroblasts calmer, supports collagen preservation, and maintains a stronger, more resilient barrier,” says Thomas.

This mechanism explains its broad benefits, from maintaining hydration to supporting barrier integrity and elasticity.

SKINCARE BENEFITS OF ASTAXANTHIN

Astaxanthin offers a wide array of benefits, particularly for oxidative-stress-related concerns:

Anti-ageing: Helps reduce fine lines, improves skin elasticity and supports collagen and elastin.

Barrier support: Enhances hydration and overall skin comfort.

Calming effect: Reduces redness and environmental reactivity.

Radiance and tone: Evens skin tone and diminishes dullness.

Gardner summarises, “Regular use can help improve the appearance of fine lines, dullness and uneven tone. It also supports barrier integrity, which helps skin maintain moisture and bounce.”

CLINICAL EVIDENCE AND RESEARCH

Several clinical studies support astaxanthin’s effectiveness. Human trials have shown improvements in elasticity, smoothness, hydration and visible signs of photoageing.

A notable 10-week study by Ito et al. demonstrated that oral supplementation with 4mg of astaxanthin improved minimal erythema dose (MED) and reduced moisture loss, while also enhancing texture and roughness in non-UV-exposed skin.

Lorraine Perretta, head of nutrition at Advanced Nutrition Programme, highlights, “Astaxanthin reduces collagen and elastin breakdown, plus protects, promotes and retains collagen and elastin – the key skin structures.”

Meta-analyses also suggest that oral supplementation may offer a more sustained impact than topical application, particularly for elasticity and overall skin resilience.

WHO CAN BENEFIT FROM ASTAXANTHIN?

Astaxanthin is generally suitable for all skin types, especially those concerned with:

• Premature ageing

• UV or pollution exposure

• Sensitive or reactive skin

• Menopausal skin or barrier fragility “It’s a great choice for menopausal, stressed or urban skin,” says Gardner.

Thomas notes its particular value for photo-exposed, reactive or barrier-fragile skins, saying it’s “great for ‘city skin’, frequent flyers and retinoid-sensitive clients”.

INCORPORATING ASTAXANTHIN INTO PROFESSIONAL TREATMENTS

Astaxanthin can be introduced in antioxidant-boosting phases of facials or as a post-treatment finish to reinforce barrier recovery. It pairs synergistically with red LED therapy and should generally be applied after heat-based procedures like radiofrequency to avoid degradation.

“Position it as part of a ‘defense and recovery’ focus within treatment offerings. It’s ideal for skin exposed to pollution, blue light or UV,” says Gardner.

Pairing with other actives, such as vitamins C and E, peptides, hyaluronic acid and retinol, enhances overall skin resilience.

HOMECARE RECOMMENDATIONS

Astaxanthin is most effective in leave-on formulations like serums, moisturisers and targeted treatments.

Thomas advises, “Daily use, morning and evening, sets expectations at eight to twelve weeks for visible changes in elasticity, TEWL and texture.”

Morning application offers protection from environmental stressors, while evening use supports repair and regeneration during natural skin renewal cycles.

ORAL SUPPLEMENTATION FOR SKIN HEALTH

Oral astaxanthin supplementation provides systemic antioxidant support. A daily dose of 4mg is supported by clinical studies and is best taken with dietary fats to enhance absorption.

Combining astaxanthin with other nutrients, such as omegas, antioxidants and probiotics, can further optimise skin benefits.

“We have seen initial improvements begin in the first four weeks, with continued improvements in elasticity over longer consumption,” says Perretta.

THE FUTURE OF ASTAXANTHIN IN SKINCARE

With increasing awareness of oxidative stress and environmental damage, astaxanthin’s relevance is expected to grow in both professional and consumer skincare.

Its multi-layered antioxidant action, barrier support and compatibility with other actives make it a must-have ingredient for treatments, homecare and supplementation protocols.

“As the focus on oxidative stress and environmental stressors continues, astaxanthin’s multi-dimensional antioxidant benefits and natural origin make it increasingly relevant for both professional and retail formulations,” concludes Gardner.

This article appears in February 2026

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This article appears in...
February 2026
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DEAR READERS
Welcome to the February issue of Aesthetic Medicine
MEET THE EXPERTS
The Aesthetic Medicine editorial board’s clinical expertise and diverse range of specialities help ensure the magazine meets the needs of the readers. In this issue, we have received guidance from the following members:
HOT OFF THE PRESS
FDA approves the first GLP-1 weight loss pill
SPOTLIGHT ON… ASTAXANTHIN
Ellen Cummings explores the magic behind astaxanthin’s ability to enhance skin health, improve elasticity and defend against environmental stressors
IN CLINIC WITH DR LISA DINLEY
With a career spanning dentistry, aesthetics and advanced clinical education, Dr Lisa Dinley speaks to editor Kezia Parkins about why evidence, safety and integrity must outweigh trends, hype and follower counts
BLOCKED
Dr Ed Robinson discusses the role of dental (peri-oral sensory) nerve blocks in non-surgical aesthetic medicine
THE EVOLUTION OF THE NON-SURGICAL BLEPHAROPLASTY
As patient demand grows for subtle, surgery-free eye rejuvenation, CO₂ laser technology is emerging as a powerful tool in clinical practice. Dr Alexander Parys discusses results, recovery and real-world outcomes
BODY OF EVIDENCE
Dr Paul Charlson asks, is injectable lipolysis revolutionising non-surgical body contouring?
USING FRACTIONAL CO2 FOR NON-SURGICAL BLEPHS IN SKIN OF COLOUR
Dr Sonakshi Khorana and Dr Samantha Hills discuss fractional CO₂ laser for non-surgical blepharoplasty in skin of colour, focusing on safety, ocular protection and strategies to optimise outcomes
BEYOND GLASS SKIN
Rian Seo takes a closer look into how Korean beauty, the phenomenon leading aesthetic medicine and dermatology, differs outside of Korea
HIDRADENITIS SUPPURATIVA OVERLOOKED
Kezia Parkins speaks to experts about the underdiagnosed skin condition hidradenitis suppurativa, and how bias in dermatology leaves Black women unheard
LYMPHATIC RECOVERY
Rachel Fincham delves into bridging the gap between surgery and recovery with post-operative lymphatic therapy
PIGMENTATION IN SKIN OF COLOUR
Dr Ginni Mansberg delves into the causes, management, and the effects of pigmentation in skin of colour. tudies have confirmed that pigmentation is more common in skin of colour
EMOTIONAL BURNOUT
Could burnout be driven more by emotional strain than workload? WIAM investigates…
THE MENOPAUSE GOLD RUSH
Why aesthetic clinics should tread a careful line when it comes to menopause care by not simply cashing in on the “menopause gold rush”
BUILDING YOUR TRIBE: THE VOICES IN MY HEAD
Independent nurse prescriber Julie Scott shares how your mentors, colleagues, friends and patients shape how you practice
NHS TO PRIVATE PRACTICE NO BLUEPRINT – AND NO REDUCTION IN RESPONSIBILITY
As clinicians increasingly move beyond employed healthcare into increasingly commercial environments, Amy Bird says that governance, accountability, and professional foundations must come first
ROADMAP STRATEGY FOR 2026
Lisa Kelly shares her insights on how to futureproof your clinic for 2026 and drive sustainable growth in a competitive landscape
TRUST FIRST, TREATMENT SECOND
Jamila Begum breaks down how the consultation goes beyond the first appointment, shaping the client-practitioner relationship
ASK THE EXPERTS
What should I consider when choosing an LED device for aesthetic treatments?
HIGH-TECH FACIALS... GENEO X BESPOKE GLO₂ FACIAL
Editor Kezia Parkins visited AM Awards Finalist 2025 nurse Teresa Tan to experience the Geneo X bespoke facial for deep hydration
KERALASE HAIR RESTORATION
Contributing reporter Ellen Cummings visited D.Thomas Clinic to trial the laser-based hair restoration treatment
PRODUCT NEWS
mesoestetic mesoestetic has launched axion, a new microneedling
5 MINUTES WITH… TREVOR STEYN
Kezia Parkins sat down with Esse Skincare founder Trevor Steyn to discuss the microbiome, the gut–skin axis and how modern life disrupts skin balance
CLINIC CATFISHING
Are you catfishing your patients? Derek Uittenbroek explains how to ensure your marketing matches your reality
5 LYMPHATIC DRAINAGE EXPERTS TO FOLLOW
These practitioners are carving their niche in the lymphatic drainage space
ASK ALEX
How can I make the most of the reviews for my clinic?
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