PATIENT OVERVIEW
Patient: Female Age: 41
Practitioner: Aggie Singh
Product Intervention: HYPO21 Pure Hypochlorous Solution
Treatment Duration: 2 weeks (initial phase)
Presenting Complaint: Inflammation following HA injectables
When my client arrived at the clinic, she was experiencing an acute inflammatory skin response following a cosmetic injectable procedure performed elsewhere. The product used was a hyaluronic acid-based skin booster. Within a few days post-injection, she developed widespread erythema, papular breakouts, and heightened skin sensitivity.
It’s important to clarify that I was not the practitioner who administered the injectable treatment. By the time the client presented to me, the reaction had already occurred, and she had sought advice from another professional. As part of that advice, she was prescribed benzoyl peroxide to address the breakouts. However, this intervention significantly worsened the condition. Benzoyl peroxide, being a strong keratolytic and antibacterial agent, further impaired the already compromised skin barrier, increasing transepidermal water loss (TEWL) and leading to further inflammation and discomfort.
From a clinical standpoint, such reactions post-skin booster may occur due to several mechanisms: an immune-mediated response to the product itself, microbial contamination at injection sites, or a disruption in the skin’s natural microbiome. In this case, the skin’s barrier integrity was already weakened, and the addition of a harsh topical agent disrupted its ability to repair, creating a cycle of inflammation and dysbiosis.
CLINICAL OBSERVATIONS ON PRESENTATION
During intake, the client’s skin exhibited clear signs of barrier dysfunction, including erythema, inflammation, and roughness. She was also visibly distressed, both due to the discomfort and the appearance of her skin.
• Skin appeared inflamed, stressed, and visibly congested
• Evidence of barrier compromise, likely exacerbated by overuse of active ingredients
• The client presented in a state of emotional distress related to physical discomfort and appearance.
TREATMENT PROTOCOL
The approach I chose was barrier restoration rather than active treatment. All topical actives were discontinued immediately, and I initiated a minimal intervention protocol using only HYPO21 skin spray, applied twice daily. HYPO21, containing pure hypochlorous acid, is known for its antimicrobial, anti-inflammatory, and skin-regenerative properties. The objective was to reduce microbial load, rebalance the skin microbiome, and restore the acid mantle to its physiological pH without further disruption.
No exfoliants, no serums, no makeup – this was a complete skincare reset to support the skin’s self-repair mechanisms and reduce neurogenic inflammation.
• Immediate cessation of all active skincare (including exfoliants, serums, benzoyl peroxide)
• Sole intervention: HYPO21 hypochlorous skin spray, applied twice daily
• Advised complete skin rest: No makeup, no additional products, and minimal physical disruption.
Before
After
The objective was to create a calm, healing environment both for the epidermal barrier and the neuro-immunological stress response.
CLINICAL OUTCOME AFTER TWO WEEKS
After two weeks on this simplified regimen, the client presented with a marked improvement in all symptoms. Inflammation had subsided significantly, pustular activity had resolved, and overall skin tone appeared more uniform and resilient. The texture was smoother, and her barrier function had visibly improved, indicating that the skin’s innate immunity and microbiome were beginning to normalise.
• Redness and inflammation visibly reduced
• Breakouts significantly diminished
• Skin tone more uniform and less reactive
• Texture noticeably improved, with restoration of surface hydration and comfort See comparative photographs above: pre- and post-intervention
NEXT PHASE PLAN
We are now in the process of carefully reintroducing supportive barrier-repair ingredients to maintain stability and improve skin resilience long-term and:
• Fortify barrier integrity
• Rebalance the microbiome
• Rebuild skin tolerance
• Prevent sensitisation through over-correction.
REFLECTION
This case reinforces a vital dermatological principle:
“Your skin doesn’t need to be controlled; it needs to feel safe.” In situations of iatrogenic reactivity or over-treatment, pausing to honour the skin’s innate healing intelligence, supported by a pure, stable hypochlorous acid solution can yield faster, more meaningful results than forceful corrective strategies.
This case highlights the importance of recognising when to pause aggressive treatment strategies and allow the skin to reset. HYPO21 played a key role in stabilising the skin’s pH, reducing microbial imbalance, and supporting natural barrier regeneration – ultimately allowing for a full recovery without further pharmacological intervention.
AGGIE SINGH
With two decades of experience in the aesthetics industry, Aggie Singh is a passionate advocate for understanding and treating inflammatory and compromised skin conditions from the inside out and outside in. As the founder of a specialist skincare clinic in the UK, Singh is known for her results-led approach to pigmentation, acne, sensitivity, and chronic inflammation. Singh is a multi-category winner at The Skin Games USA and now serves as a judge for the Open Medical category at The Skin Games, supporting global standards in skin health.