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Croma-Pharma® expands polynucleotide biostimulators range
Croma PhilArt now offers a line of four polynucleotide biostimulator injectable treatment options, suitable for all skin types and age groups
Croma (Croma-Pharma® GmbH) is a global player and challenger in the dynamically growing, minimally invasive aesthetics market and a leading manufacturer of premium-quality hyaluronic acid (HA) syringes. Croma’s PhilArt range restores the skin’s elasticity and promotes hydration4,7 by stimulating the body’s cell regeneration. It improves patients’ skin quality,3,5 rejuvenates the skin and makes it more radiant. Used as a foundation therapy, it also creates better outcomes for further aesthetic treatments.4
POLYNUCLEOTIDES
Stimulating cell regeneration, PhilArt is an injectable gel consisting of long-chain polynucleotides (PN). PN promote hydration of the skin1 and scavenge free radicals,2 thereby building an optimal environment for the growth of fibroblasts (cells that produce collagen).3,4 As a consequence, they promote the production of new collagen2 and elastic fibres, stimulating the body’s cell regeneration.
BASED ON NATURAL INGREDIENTS
The PN are of natural origin and derived from European freshwater fish intended for human consumption, with full control over the production chain. The manufacturing process is based on PN high purification technology (PN-HPT®), leading to a superior level of purification, thus ensuring product safety.
PROVEN SAFETY AND EFFICACY
PN have a proven safety and efficacy profile with high tolerability and low risk of adverse events,4 supported by extensive clinical data. Their use is based on more than 70 years of research and more than 100 published studies presented at national and international congresses.
PhilArt Skin Enhancement Technique (SET)Optimise patients’ skin for enhanced results with other aesthetic treatmentsPhilArt Skin
Enhancement Technique (SET) is the basic treatment enabling natural restoration for optimal skin conditions and therefore enhancing other aesthetictreatments. Infiltration with polynucleotides restores elasticity, hydration and trophism to all types of skin, regardless of age.
SET has an important role for the skin quality, restoring radiance and youthfulness, promoting regeneration and reducing wrinkles and laxity.4,7
SET generates a synergistic effect with other aesthetic procedures, such as laser,4 radiofrequency, fillers, peeling, needling and surgery.4
REFERENCES
1. Bartoletti E, Cavallini M, Maioli L, Massirone A, Palmieri IP, Papagni M et al. Introduction to polynucleotides highly purified technology. Aesthetic Medicine. 2020 Oct-Dec; Vol.7 (1): 43-47.
2. Collangelo MT. Govoni P, Beletti s, Squadrito F, Guizzardi S, Galli C. Polynucleotide bio gel enhances tissue repair, matrix disposition and organization.J. of Biological Regulators & Homeostatic Agents. 2021; Vol.35 (1): 355-362.
3. Cavallini M, Bartoletti E, Maioli L, Massirone A, Pia Palmieri I, Papagni M et al. Consensus report on the use of PN-HPT(polynucleotides highly purified technology) in aesthetic medicine.J Cosmet Dermatol. 2021 Mar. 20 (3): 922-928. doi: 10.11.11/jocd.13679. Epub 2020 Sept. 21. PMID: 32799391; PMCID: PMC7984045.
4. Cavallini M, Papagni M. Long chain polynucleotides gel and skin biorevitalisation. International Journal of Plastic Dermatology-ISPLAD. 2007; 3 (3): 27-32.
5. Massirone A. Polynucleotides highly purified technology and the face skin, a history of innovative skin priming. Aesthetic Medicine. 2021Jan-Mar; Vol. 7 (1): 25-40.
6. Araco A,Araco F. Preliminary prospective and randomised study of highly purified polynucleotide vs placebo in treatment of moderate to severe acne scars. Aesthet SurgJ. 2021Jun. 14; 41 (7): NP866-NP874. doi: 10.10.93/asj/sjab125. PMID: 33755110. PADB1222IMCAS | 38942 Product information for healthcare professionals
7. Manufacturer data on file
8. PhilArt instruction for use
For further information please contact: Croma-Pharma UK Tel: +44 118 206 6513 • E-Mail: info.uk@cromapharma.com • https://at.croma.at cromapharmauk