3 mins
PRECISION, PURITY, AND PERFORMANCE
Let’s talk about precision in medical aesthetics. Whether you’re an experienced practitioner or new to the field, you know how critical precision is for delivering patient satisfaction.
Discover Nuceiva® (botulinum toxin type A) — a neuromodulator that’s designed for precision. Nuceiva® is indicated for the temporary improvement in the appearance of moderate to severe vertical lines between the eyebrows seen at maximum frown (glabellar lines), when the severity of the above facial lines has an important psychological impact in adults below 65 years of age.1
As readers will know, Nuceiva® should only be administered by healthcare practitioners with appropriate qualifications and expertise in the treatment of glabellar lines and the use of required equipment.
Designed for Precision: It starts with the patented Hi-Pure™ technology. This unique manufacturing process yields a product that is ≥95% pure.2* That’s not just a claim; it’s backed by a rigorous manufacturing method.
• The Hi-Pure™ technology reduces impurities: By utilising a series of anion exchange chromatography columns that absorb process-related and product-related impurities, while allowing the drug substance to flow through for collection2
• The process defines the product: The process combines Hi-Pure™ technology with vacuum drying to optimise the final product quality and produce a precise product2
• Nuceiva® is a unique neuromodulator:1 As with every botulinum neuromodulator, Nuceiva® is unique and not interchangeable.
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What’s in the vial? Each vial of Nuceiva® contains 50 units of botulinum toxin type A, derived from Clostridium botulinum, along with HSA and NaCl.1 No preservatives, no unnecessary additives — just a simple, precise formula. Just store the unopened vials at 2-8ºC to maintain effectiveness (shelf-life 30 months).1
It’s all about your precise technique. Neuromodulators require precise intramuscular injection techniques to target the correct glabellar muscles and deliver the desired clinical results.1 Check in with your Evolus team for details of our latest training events.
This is where your skills meet the science to achieve patient satisfaction. In a study, just over 94% of Nuceiva® patients expressed a positive response (improved or much improved) at 30 days after treatment.3 And let’s not overlook safety. According to the label, Nuceiva® generally has a 1% rate of eyelid ptosis.1
As a practitioner, you have options. So why choose Nuceiva®? The answer lies in its combination of precision and patient satisfaction.
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See Prescribing Information (QR Code) for side-effects, contraindications, warnings, precautions and local and distant spread of toxin effects. Adverse reactions possibly related to the spread of toxin distant from the site of administration have been reported very rarely with botulinum toxin. Swallowing and breathing difficulties are serious and can result in death. Injection of this medicine is not recommended in patients with a history of dysphagia and aspiration. Patients or caregivers should be advised to seek immediate medical care if swallowing, speech or respiratory disorders arise. Keep out of the sight and reach of children.
The Nuceiva® PRESCRIBING INFORMATION, please scan QR code. Legal classification: POM List price: 50 units powder for solution for injection per vial: £75.50
This advertorial was commissioned, written and edited by Evolus for UK healthcare professionals only. March 2025 UK-P-2500007
REFERENCES
1. Nuceiva® SmPC (Accessed March 2025)
2. Daewoong Method for production of botulinum toxin. Accessed May 2024. https://patents.google.com/patent/US9512418B2/en
3. Rzany B, et al. Aesthet Surg J. 2020;40(4):413-429 *Purity specification of PrabotulinumtoxinA
Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcardor search MHRA Yellow Card in the Google Play or Apple App store. Adverse events should also be reported to Evolus International Ltd at medicalinformation@ evolus.comor 08000541302.