Aesthetic Medicine
Aesthetic Medicine


Raise your shield

Innovative DermShield™ technology has enabled NOON Aesthetics™ to develop a pharmaceutical skincare product line that contains active ingredients with unprecedentedly high concentration levels without the usual side effects that accompany them, such as irritation, burning, redness and unpleasant sensations.

DermShield TMis a technological breakthrough, but to understand how it works, we need to first understand the process from a scientific perspective.

Alpha hydroxy acids (and other acids, such as azelaic) have been used for decades in the field of cosmetics for skincare. They have been applied in treatments meant for both young and old for a variety of different skin conditions, in-home use, and for peeling when used in high concentration.

There are a number of rules when it comes to these treatments. The higher the concentration and the lower the pH, the stronger the peeling effect will be.

In the case of cosmetics, there is a receptor within the skin called a type C nociceptor. One of the purposes of this nociceptor is to detect the skin’s pH level. These receptors are similar to the nerves that detect pain. However, a slightly larger chain of effect is involved here that demands an explanation.

Within the skin, there are blood vessels, nerves and mast cells. Mast cells release histamine, which causes a rash or irritation. In the case of chemical peeling, the signal goes through the type C nociceptor, the mast cells, and finally to the spine and brain. When the signal passes through the blood vessels, it causes them to expand. This expansion causes us to develop redness. These vessels are extremely thin, and once they expand, the plasma within starts to penetrate the tissue.

The more the skin is sensitive and the higher the concentration is, the more these vessels will expand and secrete larger amounts of plasma, causing oedema to form. This, in turn, excites the mast cells, causing them to release histamine. This chain of effects is called neurogenic inflammation.

When it comes to injections, to reduce the pain involved, many numbing materials have been developed, from ointments to injections to pills. Despite these attempts at a solution, a product that prevents irritation, inflammation, redness, and other side effects haven’t been available for use with cosmetics until now.

The DermShield™ technology selectively suppresses tingling, burning, and itching has no sense of local anaesthesia in the treated area, suppresses erythema and oedema of the skin, prevents neurogenic inflammation, and suppresses the formation of cytokines responsible for the initiation of inflammation.

Using the DermShield™ technology, we apply the substance; it numbs the type C nociceptors and nerves to prevent any irritation, yet still delivers the positive effects of treatment with 15% concentration and a pH of 3.5 at daily use.

This makes Noon’s DermShield™ the only line of cosmetics that can be used daily with these high concentrations without the appearance of unwanted side effects.

By utilising DermShield™, you can provide clients with powerful peels and other treatments without them experiencing any redness, irritation, or other nasty side effects. An experience that will guarantee returning customers, make sessions more pleasant, and removes stress for all involved, allowing everyone to look their best at all times.

For more information visit or

This article appears in the June 2022 Issue of Aesthetic Medicine

Click here to view the article in the magazine.
To view other articles in this issue Click here.
If you would like to view other issues of Aesthetic Medicine, you can see the full archive here.

This article appears in the June 2022 Issue of Aesthetic Medicine